Mycobacterium avium subsp paratuberculosis strains isolated from Crohn's disease patients and animal species exhibit similar polymorphic locus patterns

被引:71
作者
Ghadiali, AH
Strother, M
Naser, SA
Manning, EJB
Sreevatsan, S
机构
[1] Ohio State Univ, FAHRP, OARDC, Wooster, OH 44691 USA
[2] Ohio State Univ, Dept Vet Prevent Med, Wooster, OH 44691 USA
[3] Univ Cent Florida, Dept Mol Biol & Microbiol, Orlando, FL USA
[4] Univ Wisconsin, Sch Vet Med, Dept Pathobiol Sci, Madison, WI USA
关键词
D O I
10.1128/JCM.42.11.5345-5348.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Analysis of short sequence repeats of Mycobacterium avium subsp. paratuberculosis isolated from Crohn's disease patients identified two alleles, both of which clustered with strains derived from animals with Johne's disease. Identification of a limited number of genotypes among human strains implies the existence of human disease-associated genotypes and strain sharing with animals.
引用
收藏
页码:5345 / 5348
页数:4
相关论文
共 19 条
[11]   Multiple-locus variable-number tandem repeat analysis reveals genetic relationships within Bacillus anthracis [J].
Keim, P ;
Price, LB ;
Klevytska, AM ;
Smith, KL ;
Schupp, JM ;
Okinaka, R ;
Jackson, PJ ;
Hugh-Jones, ME .
JOURNAL OF BACTERIOLOGY, 2000, 182 (10) :2928-2936
[12]   MEGA2: molecular evolutionary genetics analysis software [J].
Kumar, S ;
Tamura, K ;
Jakobsen, IB ;
Nei, M .
BIOINFORMATICS, 2001, 17 (12) :1244-1245
[13]   NOD2 (CARD15), the first susceptibility gene for Crohn's disease [J].
McGovern, DPB ;
Van Heel, DA ;
Ahmad, T ;
Jewell, DP .
GUT, 2001, 49 (06) :752-754
[14]   Molecular epidemiology of Mycobacterium avium subsp paratuberculosis isolates recovered from wild animal species [J].
Motiwala, AS ;
Amonsin, A ;
Strother, M ;
Manning, EJB ;
Kapur, V ;
Sreevatsan, S .
JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (04) :1703-1712
[15]   Molecular epidemiology of Mycobacterium avium subsp paratuberculosis:: Evidence for limited strain diversity, strain sharing, and identification of unique targets for diagnosis [J].
Motiwala, AS ;
Strother, M ;
Amonsin, A ;
Byrum, B ;
Naser, SA ;
Stabel, JR ;
Shulaw, WP ;
Bannantine, JP ;
Kapur, V ;
Sreevatsan, S .
JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (05) :2015-2026
[16]   Isolation of Mycobacterium avium subsp paratuberculosis from breast milk of Crohn's disease patients [J].
Naser, SA ;
Schwartz, D ;
Shafran, I .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2000, 95 (04) :1094-1095
[17]   Standardisation of restriction fragment length polymorphism analysis for Mycobacterium avium subspecies paratuberculosis [J].
Pavlik, I ;
Horvathova, A ;
Dvorska, L ;
Bartl, J ;
Svastova, P ;
du Maine, R ;
Rychlik, I .
JOURNAL OF MICROBIOLOGICAL METHODS, 1999, 38 (1-2) :155-167
[18]   Mycobacterium avium subspecies paratuberculosis is a cause of Crohn's disease [J].
Quirke, P .
GUT, 2001, 49 (06) :757-760
[19]   Use of short-term culture for identification of Mycobacterium avium subsp paratuberculosis in tissue from Crohn's disease patients [J].
Schwartz, D ;
Shafran, I ;
Romero, C ;
Piromalli, C ;
Biggerstaff, J ;
Naser, N ;
Chamberlain, W ;
Naser, SA .
CLINICAL MICROBIOLOGY AND INFECTION, 2000, 6 (06) :303-307