Exploiting the directionality of DNA: Controlled shrinkage of engineered oligonucleotide capsules

被引：43

作者：

Johnston, Angus P. R. ^{[1
]}

Caruso, Frank ^{[1
]}

机构：

[1] Univ Melbourne, Dept Chem & Biomol Engn, Ctr Nanosci & Nanotechnol, Parkville, Vic 3010, Australia

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 15期

关键词：

capsules; colloids; DNA; oligonucleotides; self-assembly;

D O I：

10.1002/anie.200605135

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Shrinking capsules: Using the directionality of DNA hybridization, DNA capsules with controllable shrinkage properties are formed (see picture). The degree of shrinkage ranges from 35-90% of the original particle volume, depending on the oligonucleotide sequences used to assemble the capsules. These capsules could find use in drug delivery and diagnostic applications. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

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页码：2677 / 2680

页数：4

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