Osprey: a network visualization system

被引:279
作者
Breitkreutz, BJ [1 ]
Stark, C [1 ]
Tyers, M [1 ]
机构
[1] Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Toronto, ON M5G 1X5, Canada
基金
加拿大健康研究院;
关键词
D O I
10.1186/gb-2003-4-3-r22
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
We have developed a software platform called Osprey for visualization and manipulation of complex interaction networks. Osprey builds data-rich graphical representations that are color-coded for gene function and experimental interaction data. Mouse-over functions allow rapid elaboration and organization of network diagrams in a spoke model format. User-defined large-scale datasets can be readily combined with Osprey for comparison of different methods.
引用
收藏
页数:4
相关论文
共 6 条
[1]   Gene Ontology: tool for the unification of biology [J].
Ashburner, M ;
Ball, CA ;
Blake, JA ;
Botstein, D ;
Butler, H ;
Cherry, JM ;
Davis, AP ;
Dolinski, K ;
Dwight, SS ;
Eppig, JT ;
Harris, MA ;
Hill, DP ;
Issel-Tarver, L ;
Kasarskis, A ;
Lewis, S ;
Matese, JC ;
Richardson, JE ;
Ringwald, M ;
Rubin, GM ;
Sherlock, G .
NATURE GENETICS, 2000, 25 (01) :25-29
[2]  
Batagelj V, 1998, CONNECTIONS, V21, P47, DOI DOI 10.1017/CB09780511996368
[3]  
CHERRY JM, 2002, SACCHAROMYCES GENOME
[4]   Functional organization of the yeast proteome by systematic analysis of protein complexes [J].
Gavin, AC ;
Bösche, M ;
Krause, R ;
Grandi, P ;
Marzioch, M ;
Bauer, A ;
Schultz, J ;
Rick, JM ;
Michon, AM ;
Cruciat, CM ;
Remor, M ;
Höfert, C ;
Schelder, M ;
Brajenovic, M ;
Ruffner, H ;
Merino, A ;
Klein, K ;
Hudak, M ;
Dickson, D ;
Rudi, T ;
Gnau, V ;
Bauch, A ;
Bastuck, S ;
Huhse, B ;
Leutwein, C ;
Heurtier, MA ;
Copley, RR ;
Edelmann, A ;
Querfurth, E ;
Rybin, V ;
Drewes, G ;
Raida, M ;
Bouwmeester, T ;
Bork, P ;
Seraphin, B ;
Kuster, B ;
Neubauer, G ;
Superti-Furga, G .
NATURE, 2002, 415 (6868) :141-147
[5]   Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry [J].
Ho, Y ;
Gruhler, A ;
Heilbut, A ;
Bader, GD ;
Moore, L ;
Adams, SL ;
Millar, A ;
Taylor, P ;
Bennett, K ;
Boutilier, K ;
Yang, LY ;
Wolting, C ;
Donaldson, I ;
Schandorff, S ;
Shewnarane, J ;
Vo, M ;
Taggart, J ;
Goudreault, M ;
Muskat, B ;
Alfarano, C ;
Dewar, D ;
Lin, Z ;
Michalickova, K ;
Willems, AR ;
Sassi, H ;
Nielsen, PA ;
Rasmussen, KJ ;
Andersen, JR ;
Johansen, LE ;
Hansen, LH ;
Jespersen, H ;
Podtelejnikov, A ;
Nielsen, E ;
Crawford, J ;
Poulsen, V ;
Sorensen, BD ;
Matthiesen, J ;
Hendrickson, RC ;
Gleeson, F ;
Pawson, T ;
Moran, MF ;
Durocher, D ;
Mann, M ;
Hogue, CWV ;
Figeys, D ;
Tyers, M .
NATURE, 2002, 415 (6868) :180-183
[6]   A biological atlas of functional maps [J].
Vidal, M .
CELL, 2001, 104 (03) :333-339