Intrinsic neuronal regulation of axon and dendrite growth

被引:73
作者
Goldberg, JL [1 ]
机构
[1] Bascom Palmer Eye Inst, McKnight Vis Res Ctr, Dept Ophthalmol, Miami, FL 33136 USA
关键词
D O I
10.1016/j.conb.2004.08.012
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Neurons extend long axons and highly branched dendrites, and our understanding of the essential regulators of these processes has advanced in recent years. In the past year, investigators have shown that transcriptional control, posttranslational degradation and signaling cascades may be master regulators of axon and dendrite elongation and branching. Thus, evidence is mounting for the importance of the intrinsic growth state of a neuron as a crucial determinant of its ability to grow, or to regenerate, axons and dendrites.
引用
收藏
页码:551 / 557
页数:7
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