The stereoselective preparation of cis and trans-1,2-difluoroethylene synthons

被引：50

作者：

Fontana, SA ^{[1
]}

Davis, CR ^{[1
]}

He, YB ^{[1
]}

Burton, DJ ^{[1
]}

机构：

[1] UNIV IOWA,DEPT CHEM,IOWA CITY,IA 52242

来源：

TETRAHEDRON | 1996年 / 52卷 / 01期

关键词：

D O I：

10.1016/0040-4020(95)00861-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Isomerization of (Z)-HFC=CFSiEt(3) with ultraviolet light and catalytic phenyl disulfide has resulted in a high yield, stereoselective preparation of cis-1,2-difluorotriethylsilylethylene, (E)-HFC=CFSiEt(3). (E)-HFC=CFSiEt(3) has been converted to (Z)-F(Bu(3)Sn)C=CFSiEt(3), (Z)-IFC=CFSiEt(3), (Z)-BrFC=CFSiEt(3), (Z)-Me(3)SiFC=CFSiEt(3), and (Z)-IFC=CFI. (E)-IFC=CFI has been prepared from (Z)-HFC=CFSiEt(3).

引用

页码：37 / 44

页数：8

共 15 条

[1] VITAMIN-A ISOMERS .15. THE PREPARATION OF VICINAL DIFLUOROOLEFINIC CARBONYL-COMPOUNDS AND THEIR APPLICATION TO THE SYNTHESIS OF DIFLUOROETINAL ANALOGS [J].