Modulation of host immune responses by clinically relevant human DNA and RNA viruses

被引：10

作者：

Brander, C ^{[1
]}

Walker, BD ^{[1
]}

机构：

[1] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Partners AIDS Res Ctr, Charlestown, MA 02129 USA

来源：

CURRENT OPINION IN MICROBIOLOGY | 2000年 / 3卷 / 04期

关键词：

D O I：

10.1016/S1369-5274(00)00108-9

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Numerous mechanisms allow viruses to evade host immune surveillance, and new evasion strategies continue to be identified. In addition to interference with antigen processing and presentation, direct viral modulation of host immune responses can also be achieved by altering the host cytokine milieu and the development of immunoregulatory cells. A better understanding of these viral evasion strategies will help to define critical host defense mechanisms and will lead to novel immune-based therapeutic strategies in the future.

引用

页码：379 / 386

页数：8

共 106 条

[51] The virion host shutoff function of herpes simplex virus degrades the 5′ end of a target mRNA before the 3′ end [J].