An eight-cysteine-containing CFEM domain unique to a group of fungal membrane proteins

被引：236

作者：

Kulkarni, RD

Kelkar, HS

Dean, RA

机构：

[1] N Carolina State Univ, Fungal Genomics Lab, Ctr Integrated Fungal Res, Raleigh, NC 27695 USA

[2] Univ N Carolina, Sch Med, Ctr Bioinformat, Chapel Hill, NC 27599 USA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2003年 / 28卷 / 03期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0968-0004(03)00025-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

CFEM, an eight cysteine-containing domain, has been identified by analyzing over 25 fungal sequences selected from database sequence searches. Features of CFEM suggest that it is a novel domain with characteristics distinct from known cysteine-rich domains. Some CFEM-containing proteins (e.g. Pth11 from Magnaporthe grisea) are proposed to have important roles in fungal pathogenesis.

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收藏

页码：118 / 121

页数：4

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