Minocycline-ethylenediaminetetraacetate lock solution for the prevention of implantable port infections in children with cancer

被引：59

作者：

Chatzinikolaou, I

Zipf, TF

Hanna, H

Umphrey, J

Roberts, WM

Sherertz, R

Hachem, R

Raad, I

机构：

[1] Univ Texas, MD Anderson Canc Ctr, Dept Infect Dis Infect Control & Employee Hlth, Div Internal Med, Houston, TX 77030 USA

[2] Childrens Hosp, Emergency Ctr, Houston, TX USA

[3] Miller Childrens Hosp, Jonathan Jaques Childrens Canc Ctr, Long Beach, CA USA

[4] Wake Forest Univ, Bowman Gray Sch Med, Dept Internal Med, Infect Dis Sect, Winston Salem, NC 27103 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2003年 / 36卷 / 01期

关键词：

D O I：

10.1086/344952

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In this prospective cohort study, minocycline-ethylenediaminetetraacetate (M-EDTA) was used as a lock solution in indwelling ports inserted in 14 children with cancer. No port infections, thrombotic events, or other adverse events were observed, compared with 10 port infections that occurred in 48 control patients whose ports were flushed with heparin. M-EDTA is a promising lock solution in long-term catheters.

引用

页码：116 / 119

页数：4

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