A brief history of the randomized controlled trial - From oranges and lemons to the gold standard

被引：120

作者：

Meldrum, ML ^{[1
]}

机构：

[1] Natl Inst Dent & Craniofacial Res, Pain & Neurosensory Mechanisms Branch, NIH, Bethesda, MD USA

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2000年 / 14卷 / 04期

关键词：

D O I：

10.1016/S0889-8588(05)70309-9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This article discusses the history and development of randomized clinical trial methodology, the reasons for its status and authority as a method of therapeutic evaluation, and the continuing role of clinical judgement in designing, interpreting, and applying the findings of trials.

引用

页码：745 / +

页数：17

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