Functional modulation of the sodium pump: The regulatory proteins "fixit"

被引：65

作者：

Cornelius, F ^{[1
]}

Mahmmoud, YA ^{[1
]}

机构：

[1] Aarhus Univ, Dept Biophys, DK-8000 Aarhus, Denmark

来源：

NEWS IN PHYSIOLOGICAL SCIENCES | 2003年 / 18卷

关键词：

D O I：

10.1152/nips.01434.2003

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Proteins of the FXYD family act as tissue-specific regulators of the Na-K-ATPase. They are small hydrophobic type I proteins with a single-transmembrane span containing an extracellular invariant FXYD sequence. FXYD proteins are not an integral part of the Na-K-ATPase but function to modulate its catalytic properties by molecular interactions with specific Na-K-ATPase domains.

引用

页码：119 / 124

页数：6

共 16 条

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