Integrating computationally assembled mouse transcript sequences with the Mouse Genome Informatics (MGI) database

被引:16
作者
Zhu, YX
King, BL
Parvizi, B
Brunk, BP
Stoeckert, CJ
Quackenbush, J
Richardson, J
Bult, CJ
机构
[1] Jackson Lab, Bar Harbor, ME 04609 USA
[2] Invitrogen Corp, Carlsbad, CA 92008 USA
[3] Univ Penn, Ctr Bioinformat, Philadelphia, PA 19104 USA
[4] Inst Genom Res, Rockville, MD 20850 USA
关键词
D O I
10.1186/gb-2003-4-2-r16
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Databases of experimentally generated and computationally derived transcript sequences are valuable resources for genome analysis and annotation. The utility of such databases is enhanced when the sequences they contain are integrated with such biological information as genomic location, gene function, gene expression and phenotypic variation. We present the analysis and results of a semi-automated process of connecting transcript assemblies with highly curated biological information for mouse genes that is available through the Mouse Genome Informatics (MGI) database.
引用
收藏
页数:8
相关论文
共 32 条
  • [1] Gene Ontology: tool for the unification of biology
    Ashburner, M
    Ball, CA
    Blake, JA
    Botstein, D
    Butler, H
    Cherry, JM
    Davis, AP
    Dolinski, K
    Dwight, SS
    Eppig, JT
    Harris, MA
    Hill, DP
    Issel-Tarver, L
    Kasarskis, A
    Lewis, S
    Matese, JC
    Richardson, JE
    Ringwald, M
    Rubin, GM
    Sherlock, G
    [J]. NATURE GENETICS, 2000, 25 (01) : 25 - 29
  • [2] DIFFERENTIAL SPLICING AND ALTERNATIVE POLYADENYLATION GENERATES DISTINCT NCAM TRANSCRIPTS AND PROTEINS IN THE MOUSE
    BARBAS, JA
    CHAIX, JC
    STEINMETZ, M
    GORIDIS, C
    [J]. EMBO JOURNAL, 1988, 7 (03) : 625 - 632
  • [3] The Mouse Genome Database (MGD): the model organism database for the laboratory mouse
    Blake, JA
    Richardson, JE
    Bult, CJ
    Kadin, JA
    Eppig, JT
    [J]. NUCLEIC ACIDS RESEARCH, 2002, 30 (01) : 113 - 115
  • [4] ESTABLISHING A HUMAN TRANSCRIPT MAP
    BOGUSKI, MS
    SCHULER, GD
    [J]. NATURE GENETICS, 1995, 10 (04) : 369 - 371
  • [5] Mouse genome informatics in a new age of biological inquiry
    Bult, CJ
    Richardson, JE
    Blake, JA
    Kadin, JA
    Ringwald, M
    [J]. IEEE INTERNATIONAL SYMPOSIUM ON BIO-INFORMATICS AND BIOMEDICAL ENGINEERING, PROCEEDINGS, 2000, : 29 - 32
  • [6] STACK: Sequence Tag Alignment and Consensus Knowledgebase
    Christoffels, A
    van Gelder, A
    Greyling, G
    Miller, R
    Hide, T
    Hide, W
    [J]. NUCLEIC ACIDS RESEARCH, 2001, 29 (01) : 234 - 238
  • [7] Mouse eosinophil-associated ribonucleases: a unique subfamily expressed during hematopoiesis
    Cormier, SA
    Larson, KA
    Yuan, SB
    Mitchell, TL
    Lindenberger, K
    Carrigan, P
    Lee, NA
    Lee, JJ
    [J]. MAMMALIAN GENOME, 2001, 12 (05) : 352 - 361
  • [8] INTERACTION AND SEQUENCE DIVERSITY AMONG T15 VH GENES IN CBA/J MICE
    FERGUSON, SE
    RUDIKOFF, S
    OSBORNE, BA
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1988, 168 (04) : 1339 - 1349
  • [9] An imprinted, mammalian bicistronic transcript encodes two independent proteins
    Gray, TA
    Saitoh, S
    Nicholls, RD
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (10) : 5616 - 5621
  • [10] Tissue-selective expression of α-dystrobrevin is determined by multiple promoters
    Holzfeind, PJ
    Ambrose, HJ
    Newey, SE
    Nawrotzki, RA
    Blake, DJ
    Davies, KE
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (10) : 6250 - 6258