Synthesis and antibacterial activity of metal complexes of ciprofloxacin

被引：84

作者：

Anacona, JR ^{[1
]}

Toledo, C ^{[1
]}

机构：

[1] Univ Oriente, Dept Quim, Cumana, Venezuela

来源：

TRANSITION METAL CHEMISTRY | 2001年 / 26卷 / 1-2期

关键词：

D O I：

10.1023/A:1007154817081

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The interactions of ciprofloxacin (HCipro) with transition metals have been investigated. Two types of complexes, [M(Cipro)(OAc)(H2O)(2)] . 3H(2)O (M = Mn-II, Co-II, Cu-II or (CdI)-I-I) and [M(Cipro)(OAc)] . 6H(2)O (M = Ni-II or Zn-II), were obtained and characterized by physicochemical and spectroscopic methods. The i.r. spectra of the complexes suggest that the ciprofloxacin behaves as a monoanionic bidentate ligand. In vitro antibacterial activities of the HCipro and the complexes were tested.

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页码：228 / 231

页数：4

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