Single- and double-stranded DNA: building a trigger of ATR-mediated DNA damage response

被引:97
作者
Zou, Lee [1 ]
机构
[1] Massachusetts Gen Hosp, Ctr Canc, Charlestown, MA 02129 USA
[2] Harvard Univ, Sch Med, Dept Pathol, Charlestown, MA 02129 USA
关键词
hints from yeast; Xenopus; and human;
D O I
10.1101/gad.1550307
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
[No abstract available]
引用
收藏
页码:879 / 885
页数:7
相关论文
共 54 条
[1]   ATR couples FANCD2 monoubiquitination to the DNA-damage response [J].
Andreassen, PR ;
D'Andrea, AD ;
Taniguchi, T .
GENES & DEVELOPMENT, 2004, 18 (16) :1958-1963
[2]   ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation [J].
Ball, HL ;
Myers, JS ;
Cortez, D .
MOLECULAR BIOLOGY OF THE CELL, 2005, 16 (05) :2372-2381
[3]   ATRIP oligomerization is required for ATR-dependent checkpoint signaling [J].
Ball, HL ;
Cortez, D .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (36) :31390-31396
[4]   Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro [J].
Bermudez, VP ;
Lindsey-Boltz, LA ;
Cesare, AJ ;
Maniwa, Y ;
Griffith, JD ;
Hurwitz, J ;
Sancar, A .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (04) :1633-1638
[5]   Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint [J].
Byun, TS ;
Pacek, M ;
Yee, MC ;
Walter, JC ;
Cimprich, KA .
GENES & DEVELOPMENT, 2005, 19 (09) :1040-1052
[6]   Repeated phosphopeptide motifs in human claspin are phosphorylated by Chk1 and mediate claspin function [J].
Chini, Claudia C. S. ;
Chen, Junjie .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (44) :33276-33282
[7]   An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication [J].
Costanzo, V ;
Shechter, D ;
Lupardus, PJ ;
Cimprich, KA ;
Gottesman, M ;
Gautier, J .
MOLECULAR CELL, 2003, 11 (01) :203-213
[8]   ATM regulates ATR chromatin loading in response to DNA double-strand breaks [J].
Cuadrado, M ;
Martinez-Pastor, B ;
Murga, M ;
Toledo, LI ;
Gutierrez-Martinez, P ;
Lopez, E ;
Fernandez-Capetillo, O .
JOURNAL OF EXPERIMENTAL MEDICINE, 2006, 203 (02) :297-303
[9]   A Rad3-Rad26 complex responds to DNA damage independently of other checkpoint proteins [J].
Edwards, RJ ;
Bentley, NJ ;
Carr, AM .
NATURE CELL BIOLOGY, 1999, 1 (07) :393-398
[10]   Biochemical characterization of DNA damage checkpoint complexes:: Clamp loader and clamp complexes with specificity for 5′ recessed DNA [J].
Ellison, V ;
Stillman, B .
PLOS BIOLOGY, 2003, 1 (02) :231-243