Gene silencing: Shrinking the black box of RNAi

被引：37

作者：

Hunter, CP ^{[1
]}

机构：

[1] Harvard Univ, Dept Mol & Cellular Biol, Cambridge, MA 02138 USA

来源：

CURRENT BIOLOGY | 2000年 / 10卷 / 04期

关键词：

D O I：

10.1016/S0960-9822(00)00325-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The mysterious mechanism whereby the mere presence of double-stranded RNA can Inactivate specific genes is yielding its secrets. Recent results identifying cellular components required for RNAi in Caenorhabditis elegans Indicate that the mechanism is conserved, ancient and may provide a defense against selfish DNA.

引用

页码：R137 / R140

页数：4

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