Specialization of tumour vasculature

被引：558

作者：

Ruoslahti, E ^{[1
]}

机构：

[1] Burnham Inst, Ctr Canc Res, La Jolla, CA 92037 USA

来源：

NATURE REVIEWS CANCER | 2002年 / 2卷 / 02期

关键词：

D O I：

10.1038/nrc724

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Tumour blood vessels express markers that are not present in resting blood vessels of normal tissues, but that can be shared by angiogenic vessels in non-malignant conditions. Many of these proteins are functionally important in the angiogenic process. Some tumours also contain lymphatic vessels, as well as channels that consist of cancer cells and their extracellular matrix. These special features of tumour vessels are good targets for cancer therapies.

引用

页码：83 / 90

页数：8

共 82 条

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