The essential role of chemokines in the selective regulation of lymphocyte homing

被引：44

作者：

Rosa Bono, Maria ^{[1
]}

Elgueta, Raul ^{[1
]}

Sauma, Daniela ^{[1
]}

Pino, Karina ^{[1
]}

Osorio, Fabiola ^{[1
]}

Michea, Paula ^{[1
]}

Fierro, Alberto ^{[1
]}

Rosemblatt, Mario ^{[1
]}

机构：

[1] Univ Chile, Fac Ciencias, Dept Biol, Santiago, Chile

来源：

CYTOKINE & GROWTH FACTOR REVIEWS | 2007年 / 18卷 / 1-2期

关键词：

lymphocyte homing; chemokines;

D O I：

10.1016/j.cytogfr.2007.01.004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Knowledge of lymphocyte migration has become a major issue in our understanding of acquired immunity. The selective migration of naive, effector, memory and regulatory T-cells is a multiple step process regulated by a specific arrangement of cytokines, chemokines and adhesion receptors that guide these cells to specific locations. Recent research has outlined two major pathways of lymphocyte trafficking under homeostatic and inflammatory conditions, one concerning tropism to cutaneous tissue and a second one related to mucosal-associated sites. In this article we will outline our present understanding of the role of cytokines and chemokines as regulators of lymphocyte migration through tissues. (c) 2007 Published by Elsevier Ltd.

引用

页码：33 / 43

页数：11

共 94 条

[21] Tissue targeting of T cells by DCs and microenvironments [J].

Dudda, JC ;

Martin, SF .

TRENDS IN IMMUNOLOGY, 2004, 25 (08) :417-421

[22] Dendritic cell immunization route determines CD8+ T cell trafficking to inflamed skin:: Role for tissue microenvironment and dendritic cells in establishment of T cell-homing subsets [J].

Dudda, JC ;

Simon, JC ;

Martin, S .

JOURNAL OF IMMUNOLOGY, 2004, 172 (02) :857-863

[23] Hepatic endothelial CCL25 mediates the recruitment of CCR9+ gut-homing lymphocytes to the liver in primary sclerosing cholangitis [J].

Eksteen, B ;

Grant, AJ ;

Miles, A ;

Curbishley, SM ;

Lalor, PF ;

Hübscher, SG ;

Briskin, M ;

Salmon, M ;

Adams, DH .

JOURNAL OF EXPERIMENTAL MEDICINE, 2004, 200 (11) :1511-1517

[24] Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10 [J].

Eksteen, Bertus ;

Miles, Alice ;

Curbishley, Stuart M. ;

Tselepis, Chris ;

Grant, Allister J. ;

Walker, Lucy S. K. ;

Adams, David H. .

JOURNAL OF IMMUNOLOGY, 2006, 177 (01) :593-603

[25] Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state [J].

Fisson, S ;

Darrasse-Jèze, G ;

Litvinova, E ;

Septier, F ;

Klatzmann, D ;

Liblau, R ;

Salomon, BL .

JOURNAL OF EXPERIMENTAL MEDICINE, 2003, 198 (05) :737-746

[26] Preferential migration of effector CD8+ T cells into the interstitium of the normal lung [J].

Galkina, E ;

Thatte, J ;

Dabak, V ;

Williams, MB ;

Ley, K ;

Braciale, TJ .

JOURNAL OF CLINICAL INVESTIGATION, 2005, 115 (12) :3473-3483

[27] ROUTE OF RE-CIRCULATION OF LYMPHOCYTES IN RAT [J].

GOWANS, JL ;

KNIGHT, EJ .

PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1964, 159 (975) :257-+

[28] Identification of regulatory T cells in tolerated allografts [J].

Graca, L ;

Cobbold, SP ;

Waldmann, H .

JOURNAL OF EXPERIMENTAL MEDICINE, 2002, 195 (12) :1641-1646

[29] Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization [J].

Gunn, MD ;

Kyuwa, S ;

Tam, C ;

Kakiuchi, T ;

Matsuzawa, A ;

Williams, LT ;

Nakano, H .

JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 189 (03) :451-460

[30] A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes [J].

Gunn, MD ;

Tangemann, K ;

Tam, C ;

Cyster, JG ;

Rosen, SD ;

Williams, LT .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (01) :258-263

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