Transcription, genomes, function

被引:109
作者
Cho, RJ
Campbell, MJ
机构
[1] Stanford Univ, Sch Med, Dept Genet, Stanford, CA 94035 USA
[2] Stanford Univ, Sch Med, Dept Biochem, Stanford, CA 94035 USA
[3] Celera Genom Inc, Foster City, CA 94404 USA
关键词
D O I
10.1016/S0168-9525(00)02065-5
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Large-scale studies of mRNA expression have displayed the unusual ability to both challenge traditional biological paradigms and enjoy rapid adoption among a wide range of researchers. The proliferating applications of this technology are poised to exert heavy influence on the very way biologists conceptualize problems and ask questions in the post-genome era.
引用
收藏
页码:409 / 415
页数:7
相关论文
共 60 条
  • [51] Characterization of the yeast transcriptome
    Velculescu, VE
    Zhang, L
    Zhou, W
    Vogelstein, J
    Basrai, MA
    Bassett, DE
    Hieter, P
    Vogelstein, B
    Kinzler, KW
    [J]. CELL, 1997, 88 (02) : 243 - 251
  • [52] Analysis of human transcriptomes
    Velculescu, VE
    Madden, SL
    Zhang, L
    Lash, AE
    Yu, J
    Rago, C
    Lal, A
    Wang, CJ
    Beaudry, GA
    Ciriello, KM
    Cook, BP
    Dufault, MR
    Ferguson, AT
    Gao, YH
    He, TC
    Hermeking, H
    Hiraldo, SK
    Hwang, PM
    Lopez, MA
    Luderer, HF
    Mathews, B
    Petroziello, JM
    Polyak, K
    Zawel, L
    Zhang, W
    Zhang, XM
    Zhou, W
    Haluska, FG
    Jen, J
    Sukumar, S
    Landes, GM
    Riggins, GJ
    Vogelstein, B
    Kinzler, KW
    [J]. NATURE GENETICS, 1999, 23 (04) : 387 - 388
  • [53] An information-intensive approach to the molecular pharmacology of cancer
    Weinstein, JN
    Myers, TG
    OConnor, PM
    Friend, SH
    Fornace, AJ
    Kohn, KW
    Fojo, T
    Bates, SE
    Rubinstein, LV
    Anderson, NL
    Buolamwini, JK
    vanOsdol, WW
    Monks, AP
    Scudiero, DA
    Sausville, EA
    Zaharevitz, DW
    Bunow, B
    Viswanadhan, VN
    Johnson, GS
    Wittes, RE
    Paull, KD
    [J]. SCIENCE, 1997, 275 (5298) : 343 - 349
  • [54] Microarray analysis of Drosophila development during metamorphosis
    White, KP
    Rifkin, SA
    Hurban, P
    Hogness, DS
    [J]. SCIENCE, 1999, 286 (5447) : 2179 - 2184
  • [55] Functional analysis of the yeast genome
    Winzeler, EA
    Davis, RW
    [J]. CURRENT OPINION IN GENETICS & DEVELOPMENT, 1997, 7 (06) : 771 - 776
  • [56] Genome-wide expression monitoring in Saccharomyces cerevisiae
    Wodicka, L
    Dong, HL
    Mittmann, M
    Ho, MH
    Lockhart, DJ
    [J]. NATURE BIOTECHNOLOGY, 1997, 15 (13) : 1359 - 1367
  • [57] Wolfsberg TG, 1999, GENOME RES, V9, P775
  • [58] Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast
    Wyrick, JJ
    Holstege, FCP
    Jennings, EG
    Causton, HC
    Shore, D
    Grunstein, M
    Lander, ES
    Young, RA
    [J]. NATURE, 1999, 402 (6760) : 418 - 421
  • [59] Genomic cis-regulatory logic: Experimental and computational analysis of a sea urchin gene
    Yuh, CH
    Bolouri, H
    Davidson, EH
    [J]. SCIENCE, 1998, 279 (5358) : 1896 - 1902
  • [60] Gene expression profiles in normal and cancer cells
    Zhang, L
    Zhou, W
    Velculescu, VE
    Kern, SE
    Hruban, RH
    Hamilton, SR
    Vogelstein, B
    Kinzler, KW
    [J]. SCIENCE, 1997, 276 (5316) : 1268 - 1272