The European Bioinformatics Institute's data resources

被引：32

作者：

Brooksbank, C ^{[1
]}

Camon, E ^{[1
]}

Harris, MA ^{[1
]}

Magrane, M ^{[1
]}

Martin, MJ ^{[1
]}

Mulder, N ^{[1
]}

O'Donovan, C ^{[1
]}

Parkinson, H ^{[1
]}

Tuli, MA ^{[1
]}

Apweiler, R ^{[1
]}

Birney, E ^{[1
]}

Brazma, A ^{[1
]}

Henrick, K ^{[1
]}

Lopez, R ^{[1
]}

Stoesser, G ^{[1
]}

Stoehr, P ^{[1
]}

Cameron, G ^{[1
]}

机构：

[1] European Bioinformat Inst, EMBL, Cambridge CB10 1SD, England

来源：

NUCLEIC ACIDS RESEARCH | 2003年 / 31卷 / 01期

基金：

英国惠康基金; 英国医学研究理事会; 英国工程与自然科学研究理事会;

关键词：

D O I：

10.1093/nar/gkg066

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

As the amount of biological data grows, so does the need for biologists to store and access this information in central repositories in a free and unambiguous manner. The European Bioinformatics Institute (EBI) hosts six core databases, which store information on DNA sequences (EMBL-Bank), protein sequences (SWISS-PROT and TrEMBL), protein structure (MSD), whole genomes (Ensembl) and gene expression (ArrayExpress). But just as a cell would be useless if it couldn't transcribe DNA or translate RNA, our resources would be compromised if each existed in isolation. We have therefore developed a range of tools that not only facilitate the deposition and retrieval of biological information, but also allow users to carry out searches that reflect the interconnectedness of biological information. The EBI's databases and tools are all available on our website at www.ebi.ac.uk.

引用

页码：43 / 50

页数：8

共 35 条

[1]

Altschul SF, 1996, METHOD ENZYMOL, V266, P460

[2] Gapped BLAST and PSI-BLAST: a new generation of protein database search programs [J].

Altschul, SF ;

Madden, TL ;

Schaffer, AA ;

Zhang, JH ;

Zhang, Z ;

Miller, W ;

Lipman, DJ .

NUCLEIC ACIDS RESEARCH, 1997, 25 (17) :3389-3402

[3] Microarray standards at last -: Not a moment too soon, the microarray community has issued guidelines that will make their data much more useful and accessible.: Nature and the Nature research journals will respond accordingly. [J].

不详 .

NATURE, 2002, 419 (6905) :323-323

[4]

Apweiler R, 2001, Brief Bioinform, V2, P9, DOI 10.1093/bib/2.1.9

[5] The InterPro database, an integrated documentation resource for protein families, domains and functional sites [J].

Apweiler, R ;

Attwood, TK ;

Bairoch, A ;

Bateman, A ;

Birney, E ;

Biswas, M ;

Bucher, P ;

Cerutti, T ;

Corpet, F ;

Croning, MDR ;

Durbin, R ;

Falquet, L ;

Fleischmann, W ;

Gouzy, J ;

Hermjakob, H ;

Hulo, N ;

Jonassen, I ;

Kahn, D ;

Kanapin, A ;

Karavidopoulou, Y ;

Lopez, R ;

Marx, B ;

Mulder, NJ ;

Oinn, TM ;

Pagni, M ;

Servant, F ;

Sigrist, CJA ;

Zdobnov, EM .

NUCLEIC ACIDS RESEARCH, 2001, 29 (01) :37-40

[6]

Ashburner M, 2001, GENOME RES, V11, P1425

[7] Gene Ontology: tool for the unification of biology [J].

Ashburner, M ;

Ball, CA ;

Blake, JA ;

Botstein, D ;

Butler, H ;

Cherry, JM ;

Davis, AP ;

Dolinski, K ;

Dwight, SS ;

Eppig, JT ;

Harris, MA ;

Hill, DP ;

Issel-Tarver, L ;

Kasarskis, A ;

Lewis, S ;

Matese, JC ;

Richardson, JE ;

Ringwald, M ;

Rubin, GM ;

Sherlock, G .

NATURE GENETICS, 2000, 25 (01) :25-29

[8] PRINTS and PRINTS-S shed light on protein ancestry [J].

Attwood, TK ;

Blythe, MJ ;

Flower, DR ;

Gaulton, A ;

Mabey, JE ;

Maudling, N ;

McGregor, L ;

Mitchell, AL ;

Moulton, G ;

Paine, K ;

Scordis, P .

NUCLEIC ACIDS RESEARCH, 2002, 30 (01) :239-241

[9] The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000 [J].

Bairoch, A ;

Apweiler, R .

NUCLEIC ACIDS RESEARCH, 2000, 28 (01) :45-48

[10]

Bateman A, 2004, NUCLEIC ACIDS RES, V32, pD138, DOI [10.1093/nar/gkp985, 10.1093/nar/gkh121, 10.1093/nar/gkr1065]

← 1 2 3 4 →