Overrepresentation of a gene family encoding extracytoplasmic solute receptors in Bordetella

被引：55

作者：

Antoine, R

Jacob-Dubuisson, F

Drobecq, H

Willery, E

Lesjean, S

Locht, C

机构：

[1] Inst Pasteur, INSERM U447, IBL, F-59019 Lille, France

[2] Inst Pasteur, CNRS UMR 8525, Inst Biol Lille, F-59019 Lille, France

来源：

JOURNAL OF BACTERIOLOGY | 2003年 / 185卷 / 04期

关键词：

D O I：

10.1128/JB.185.4.1470-1474.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A family of genes that are likely to encode extracytoplasmic salute receptors is strongly overrepresented in several beta-proteabacteria, including Bordetella pertussis. This gene family, of which members have been called bug genes, contains some examples that are contained within polycistronic operons coding far tripartite uptake transporters of the TIT family, while the vast majority are "orphan" genes. Proteomic and functional analyses demonstrated that several of these genes are expressed in B. pertussis, and one is involved in citrate uptake. The bug genes probably form an ancient family that has been subjected to a large expansion to a restricted phytogenic group.

引用

页码：1470 / 1474

页数：5

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