Spread of OXA-48-Encoding Plasmid in Turkey and Beyond

被引：221

作者：

Carrer, Amelie ^{[1
]}

Poirel, Laurent ^{[1
]}

Yilmaz, Mesut ^{[2
]}

Akan, Oezay Arikan ^{[3
]}

Feriha, Cilli ^{[4
]}

Cuzon, Gaelle ^{[1
]}

Matar, Ghassan ^{[5
]}

Honderlick, Patrick ^{[6
]}

Nordmann, Patrice ^{[1
]}

机构：

[1] Hop Bicetre, Serv Bacteriol Virol, INSERM,AP HP, Emerging Resistance Antibiot U914,Fac Med Paris S, K Bicetre, France

[2] Istanbul Univ, Cerrahpasa Med Fac, Infect Dis & Clin Microbiol Dept, Istanbul, Turkey

[3] Ankara Univ, Sch Med, Cent Labs, Ibni Sina Hosp, TR-06100 Ankara, Turkey

[4] Ege Univ, Fac Med, Dept Microbiol & Clin Microbiol, Izmir, Turkey

[5] Amer Univ Beirut, Beirut, Lebanon

[6] Hop Foch, Microbiol Serv, Suresnes, France

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2010年 / 54卷 / 03期

关键词：

OXACILLINASE-MEDIATED RESISTANCE; D BETA-LACTAMASE; KLEBSIELLA-PNEUMONIAE; IDENTIFICATION; CARBAPENEMASES; ENTEROBACTERIACEAE; ISTANBUL; IMIPENEM; OXA-48;

D O I：

10.1128/AAC.01312-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Eighteen carbapenem-resistant, OXA-48-positive enterobacterial isolates recovered from Turkey, Lebanon, Egypt, France, and Belgium were analyzed. In most isolates, similar 70-kb plasmids carrying the carbapenemase gene bla(OXA-48) were identified. That gene was located within either transposon Tn1999 or transposon Tn1999.2, which was always inserted within the same gene. This work highlights the current plasmid-mediated dissemination of the OXA-48 carbapenemase worldwide.

引用

页码：1369 / 1373

页数：5

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