A reagentless electrochemical biosensor based on a protein scaffold

被引：21

作者：

Jhaveri, SD ^{[1
]}

Mauro, JM ^{[1
]}

Goldston, HM ^{[1
]}

Schauer, CL ^{[1
]}

Tender, LM ^{[1
]}

Trammell, SA ^{[1
]}

机构：

[1] USN, Res Lab, Ctr Biomol Sci & Engn, Washington, DC 20375 USA

来源：

CHEMICAL COMMUNICATIONS | 2003年 / 03期

关键词：

D O I：

10.1039/b209452e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Apo-myoglobin, labeled with the environmentally sensitive redox probe Ru-II (NH3)(4)(1,10-phenanthroline-5-maleimide)(2+), was immobilized onto gold electrodes modified with 11-mercaptoundecanoic acid and subsequently labeled with biotin; avidin binding to the immobilized biotin was specifically and quantitatively detected by a change in cyclic voltammetry of the co-immobilized probe.

引用

页码：338 / 339

页数：2

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