T-cell subsets: Transcriptional control in the Th1/Th2 decision

被引:56
作者
Rincon, M
Flavell, RA
机构
[1] UNIV VERMONT,DEPT MED,BURLINGTON,VT 05405
[2] YALE UNIV,SCH MED,HOWARD HUGHES MED INST,NEW HAVEN,CT 06520
关键词
D O I
10.1016/S0960-9822(06)00368-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Transcriptional mechanisms in CD4(+) T cells and antigen-presenting cells determine the activation or differentiation of Th1 and Th2 helper cell subsets, and also form attractive targets for therapeutic intervention in the balance of Th1/Th2 responses. (C) Current Biology Ltd ISSN 0960-9822.
引用
收藏
页码:R729 / R732
页数:4
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