Neurobiology of panic disorder

被引：62

作者：

Bourin, M

Baker, GB

Bradwejn, J

机构：

[1] Fac Med, GIS Medicament, Grp Rech Neurobiol Anxiete ER 302, Nantes, France

[2] Univ Alberta, Dept Psychiat, Neurochem Res Unit, Edmonton, AB, Canada

[3] Clarke Inst Psychiat, Psychobiol & Clin Trials Res Unit Anxiety, Toronto, ON M5T 1R8, Canada

来源：

JOURNAL OF PSYCHOSOMATIC RESEARCH | 1998年 / 44卷 / 01期

关键词：

panic disorder; provocative agents; cholecystokinin; GABA; norepinephrine; 5-hydroxytryptamine;

D O I：

10.1016/S0022-3999(97)00203-1

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Various provocative agents, including sodium lactate, carbon dioxide (CO2), caffeine, yohimbine, serotoninergic agents, and cholecystokinin (CCK), have been utilized as panicogenics in studies on healthy volunteers as well as in panic disorder patients. An overview of the utilization of these agents to study the neurobiology of panic disorder is presented. The possible roles of several neurotransmitters and neuromodulators in the etiology of panic disorder and in the actions of drugs used in its treatment are also discussed. (C) 1998 Elsevier Science Inc.

引用

页码：163 / 180

页数：18

共 149 条

[1] CHOLECYSTOKININ IN PSYCHIATRIC RESEARCH - A TIME FOR CAUTIOUS EXCITEMENT [J].