The systemic inflammatory response, performance status and survival in patients undergoing alpha-interferon treatment for advanced renal cancer

被引:50
作者
Bromwich, E
McMillan, DC [1 ]
Lamb, GWA
Vasey, PA
Aitchison, M
机构
[1] Univ Glasgow, Royal Infirm, Dept Surg, Glasgow G31 2ER, Lanark, Scotland
[2] Gartnavel Royal Hosp, Dept Urol, Glasgow G12 0YN, Lanark, Scotland
[3] Beatson Oncol Ctr, Dept Med Oncol, Glasgow G11 6NT, Lanark, Scotland
关键词
systemic inflammatory response; C-reactive protein; performance status; survival; alpha-interferon; renal cancer;
D O I
10.1038/sj.bjc.6602152
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The prognostic value of C-reactive protein, compared with ECOG performance status (ECOG-ps), in patients receiving alpha-interferon treatment for advanced renal cancer was assessed in 58 patients. In all, 55 patients died on follow-up. On multivariate analysis with ECOG-ps and C-reactive protein entered as covariates, only C-reactive protein was a significant independent predictor of survival (HR 2.03, 95% CI 1.09-3.80, P=0.026).
引用
收藏
页码:1236 / 1238
页数:3
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