Innate immunity: Lipoproteins take their Toll on the host

被引:103
作者
Janeway, CA [1 ]
Medzhitov, R [1 ]
机构
[1] Yale Univ, Sch Med, Immunobiol Sect, New Haven, CT 06520 USA
关键词
D O I
10.1016/S0960-9822(00)80073-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A family of mammalian Toll-like receptors (TLRs) has a critical role in the recognition of microbial infection. Recent evidence suggests that bacterial lipoproteins major components of bacterial cell walls - are recognized by a member of the human TLR family.
引用
收藏
页码:R879 / R882
页数:4
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