The C7N aminocyclitol family of natural products

被引：149

作者：

Mahmud, T ^{[1
]}

机构：

[1] Univ Washington, Dept Chem, Seattle, WA 98195 USA

来源：

NATURAL PRODUCT REPORTS | 2003年 / 20卷 / 01期

关键词：

D O I：

10.1039/b205561a

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review covers microbial secondary metabolites classified in the familyof C7N aminocyclitols, a relatively new class or natural products that is increasingly. gaining recognition due to their significant biomedical and agricultural uses. Their discovery and structure determinations, their biosynthetic origin, biological properties, chemical synthesis, as well as their further development for pharmaceutical uses are described. The literature from 1970 to July 2002 is reviewed, with 269 references cited.

引用

收藏

页码：137 / 166

页数：30

相关论文

共 272 条

[21] Structure of the Aspergillus oryzae alpha-amylase complexed with the inhibitor acarbose at 2.0 angstrom resolution [J].

Brzozowski, AM ;

Davies, GJ .

BIOCHEMISTRY, 1997, 36 (36) :10837-10845

[22] Structural analysis of a chimeric bacterial α-amylase.: High-resolution analysis of native and ligand complexes [J].

Brzozowski, AM ;

Lawson, DM ;

Turkenburg, JP ;

Bisgaard-Frantzen, H ;

Svendsen, A ;

Borchert, TV ;

Dauter, Z ;

Wilson, KS ;

Davies, GJ .

BIOCHEMISTRY, 2000, 39 (31) :9099-9107

[23] Acarbose: Its role in the treatment of diabetes mellitus [J].

Campbell, LK ;

White, JR ;

Campbell, RK .

ANNALS OF PHARMACOTHERAPY, 1996, 30 (11) :1255-1262

[24] Biochemistry - Harnessing the biosynthetic code: Combinations, permutations, and mutations [J].

Cane, DE ;

Walsh, CT ;

Khosla, C .

SCIENCE, 1998, 282 (5386) :63-68

[25] INHIBITION OF HUMAN INTESTINAL ALPHA-GLUCOSIDEHYDROLASES BY A NEW COMPLEX OLIGOSACCHARIDE [J].

CASPARY, WF ;

GRAF, S .

RESEARCH IN EXPERIMENTAL MEDICINE, 1979, 175 (01) :1-6

[26] Molecular and enzymatic characterization of a maltogenic amylase that hydrolyzes and transglycosylates acarbose [J].

Cha, HJ ;

Yoon, HG ;

Kim, YW ;

Lee, HS ;

Kim, JW ;

Kweon, KS ;

Oh, BH ;

Park, KH .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1998, 253 (01) :251-262

[27] Novel α-glucosidase inhibitors, CKD-711 and CKD-711a produced by Streptomyces sp CK-4416 -: III.: Physico-chemical properties and structure elucidation [J].

Chang, HB ;

Kim, SH ;

Kwon, YI ;

Choung, DH ;

Choi, WK ;

Kang, TW ;

Lee, S ;

Kim, JG ;

Chun, HS ;

Ahn, SK ;

Hong, CI ;

Han, KH .

JOURNAL OF ANTIBIOTICS, 2002, 55 (05) :467-471

[28] STRUCTURE OF A GLYOXALASE-I INHIBITOR AND ITS CHEMICAL REACTIVITY WITH SH-COMPOUNDS [J].

CHIMURA, H ;

NAKAMURA, H ;

TAKITA, T ;

TAKEUCHI, T ;

UMEZAWA, H ;

KATO, K ;

SAITO, S ;

TOMISAWA, T ;

IITAKA, Y .

JOURNAL OF ANTIBIOTICS, 1975, 28 (10) :743-748

[29]

COGOLI A, 1975, J BIOL CHEM, V250, P7802

[30]

Coutinho PM, 1997, PROTEINS, V27, P235, DOI 10.1002/(SICI)1097-0134(199702)27:2<235::AID-PROT10>3.0.CO

← 1 2 3 4 5 6 7 8 9 10 →