Actin's many actions start at the genes

被引：17

作者：

Franke, WW ^{[1
]}

机构：

[1] German Canc Res Ctr, Div Cell Biol, D-69120 Heidelberg, Germany

来源：

NATURE CELL BIOLOGY | 2004年 / 6卷 / 11期

关键词：

D O I：

10.1038/ncb1104-1013

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Over more than three decades, sporadic and circumstantial evidence has accumulated to suggest that nuclear actin has crucial functions in RNA polymerase II-based transcription. Now, using a biochemical approach, β-actin has been identified as a highly specific, constitutive component of the active transcriptional complex required for formation of the pre-initiation transcription complex.

引用

页码：1013 / 1014

页数：2

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