Stat acetylation - A key facet of cytokine signaling?

被引:48
作者
O'Shea, JJ [1 ]
Kanno, Y
Chen, XM
Levy, DE
机构
[1] NIAMSD, NIH, Bethesda, MD 20892 USA
[2] Univ Texas, MD Anderson Canc Ctr, Dept Biochem & Mol Biol, Houston, TX 77030 USA
[3] NYU, Sch Med, Dept Pathol, New York, NY 10016 USA
[4] NYU, Sch Med, Dept Microbiol, New York, NY 10016 USA
关键词
D O I
10.1126/science.1108164
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:217 / 218
页数:2
相关论文
共 14 条
[1]   Three-dimensional structure of the Stat3β homodimer bound to DNA [J].
Becker, S ;
Groner, B ;
Müller, CW .
NATURE, 1998, 394 (6689) :145-151
[2]   Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity [J].
Chang, HM ;
Paulson, M ;
Holko, M ;
Rice, CM ;
Williams, BRG ;
Marié, I ;
Levy, DE .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (26) :9578-9583
[3]   Shaping the nuclear action of NF-κB [J].
Chen, LF ;
Greene, WC .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2004, 5 (05) :392-401
[4]   Serine phosphorylation of STATs [J].
Decker, T ;
Kovarik, P .
ONCOGENE, 2000, 19 (21) :2628-2637
[5]   Impairment of interferon-induced IRF-7 gene expression due to inhibition of ISGF3 formation by trichostatin A [J].
Génin, P ;
Morin, P ;
Civas, A .
JOURNAL OF VIROLOGY, 2003, 77 (12) :7113-7119
[6]   STATs: Transcriptional control and biological impact [J].
Levy, DE ;
Darnell, JE .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2002, 3 (09) :651-662
[7]   Cooperation of the transcriptional coactivators CBP and p300 with Stat6 [J].
McDonald, C ;
Reich, NC .
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 1999, 19 (07) :711-722
[8]   Interferon-stimulated transcription and innate antiviral immunity require deacetylase activity and histone deacetylase 1 [J].
Nusinzon, I ;
Horvath, CM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (25) :14742-14747
[9]   Cytokine signaling in 2002: New surprises in the Jak/Stat pathway [J].
O'Shea, JJ ;
Gadina, M ;
Schreiber, RD .
CELL, 2002, 109 :S121-S131
[10]   Regulation at multiple levels of NF-κB-mediated transactivation by protein acetylation [J].
Quivy, V ;
Van Lint, C .
BIOCHEMICAL PHARMACOLOGY, 2004, 68 (06) :1221-1229