Voltage-sensitive dyes for monitoring multineuronal activity in the intact central nervous system

被引:49
作者
Wu, JY [1 ]
Lam, YW
Falk, CX
Cohen, LB
Fang, J
Loew, L
Prechtl, JC
Kleinfeld, D
Tsau, Y
机构
[1] Georgetown Univ, Georgetown Inst Cognit & Computat Sci, Washington, DC 20007 USA
[2] Yale Univ, Sch Med, Dept Cellular & Mol Physiol, New Haven, CT 06520 USA
[3] Univ Connecticut, Ctr Hlth, Dept Physiol, Farmington, CT 06032 USA
[4] Univ Calif San Diego, Dept Phys 0319, La Jolla, CA 92093 USA
[5] Optimaging LLC, Fairfield, CT 06432 USA
来源
HISTOCHEMICAL JOURNAL | 1998年 / 30卷 / 03期
关键词
D O I
10.1023/A:1003295319615
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Optical monitoring of activity provides new kinds of information about brain function. Two examples are discussed in this article. First, the spike activity of many individual neurons in small ganglia can be determined. Second, the spatiotemporal characteristics of coherent activity in the brain can be directly measured. This article discusses both general characteristics of optical measurements (sources of noise) as well as more methodological aspects related to voltage-sensitive dye measurements from the nervous system. (C) 1998 Chapman & Hall.
引用
收藏
页码:169 / 187
页数:19
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