Catalytic asymmetric Horner-Wadsworth-Emmons reaction under phase-transfer-catalyzed conditions

被引：80

作者：

Arai, S ^{[1
]}

Hamaguchi, S ^{[1
]}

Shioiri, T ^{[1
]}

机构：

[1] Nagoya City Univ, Fac Pharmaceut Sci, Mizuho Ku, Nagoya, Aichi 4678603, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 19期

关键词：

asymmetric reactions; catalysts; olefination; phase transfer;

D O I：

10.1016/S0040-4039(98)00442-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The catalytic asymmetric Homer-Wadsworth-Emmons reaction promoted by quaternary ammonium salts derived from cinchonine as a phase-transfer catalyst is described. Treatment of the prochiral ketone 1 with phosphonates under mild reaction conditions afforded the corresponding desired products in moderate enantiomeric excess. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：2997 / 3000

页数：4

共 14 条

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