A double-blind, placebo controlled, dose ranging study to evaluate the safety and biological efficacy of the lipid-DNA complex GR213487B in the nasal epithelium of adult patients with cystic fibrosis

被引：28

作者：

Knowles, MR

Noone, PG

Hohneker, K

Johnson, LG

Boucher, RC

Efthimiou, J

Crawford, C

Brown, R

Schwartzbach, C

Pearlman, R

机构：

[1] Univ N Carolina, Cyst Fibrosis Ctr, Chapel Hill, NC 27599 USA

[2] Glaxo Wellcome Res & Dev Ltd, London, England

[3] Glaxo Wellcome Inc, Res Triangle Pk, NC 27709 USA

[4] Megabios Corp, Burlingame, CA 94010 USA

来源：

HUMAN GENE THERAPY | 1998年 / 9卷 / 02期

关键词：

D O I：

10.1089/hum.1998.9.2-249

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

GTAB1001: A Double-Blind, Placebo Controlled, Dose Ranging Study to Evaluate the Safety and Biological Efficacy of the Lipid-DNA Complex GR213487B in the Nasal Epithelium of Adult Patients with Cystic Fibrosis.

引用

页码：249 / 269

页数：21

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