IslandPath: aiding detection of genomic islands in prokaryotes

被引:308
作者
Hsiao, W
Wan, I
Jones, SJ
Brinkman, FSL [1 ]
机构
[1] Simon Fraser Univ, Dept Biochem & Mol Biol, Burnaby, BC V5A 1S6, Canada
[2] British Columbia Canc Agcy, Genome Sci Ctr, Vancouver, BC V5Z 4E6, Canada
关键词
D O I
10.1093/bioinformatics/btg004
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Genomic islands (clusters of genes of potential horizontal origin in a prokaryotic genome) are frequently associated with a particular adaptation of a microbe that is of medical, agricultural or environmental importance, such as antibiotic resistance, pathogen virulence, or metal resistance. While many sequence features associated with such islands have been adopted separately in applications for analysis of genomic islands, including pathogenicity islands, there is no single application that integrates multiple features for island detection. IslandPath is a network service which incorporates multiple DNA signals and genome annotation features into a graphical display of a bacterial or archaeal genome, to aid the detection of genomic islands.
引用
收藏
页码:418 / 420
页数:3
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