More kapakahines from the marine sponge cribrochalina Olemda

被引:70
作者
Nakao, Y
Kuo, J
Yoshida, WY
Kelly, M
Scheuer, PJ
机构
[1] Harbor Branch Oceanog Inst Inc, Ft Pierce, FL 34936 USA
[2] Univ Hawaii Manoa, Dept Chem, Honolulu, HI 96822 USA
关键词
D O I
10.1021/ol026830u
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
graphic Three new kapakahines E-G (1-3) have been isolated from the marine sponge Cribrochalina olemda. Limited quantities of these compounds required not only NMR analysis but also FAB-MS/MS analysis for the structure elucidation. Kapakahine E showed cytotoxicity against P388 murine leukemia cells.
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页码:1387 / 1390
页数:4
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