The possible role of bacterial superantigens in the pathogenesis of autoimmune disorders

被引：44

作者：

Schiffenbauer, J

Soos, J

Johnson, H

机构：

[1] Univ Florida, Dept Med, Gainesville, FL 32610 USA

[2] Univ Florida, Dept Microbiol & Cell Sci, Gainesville, FL 32610 USA

来源：

IMMUNOLOGY TODAY | 1998年 / 19卷 / 03期

关键词：

D O I：

10.1016/S0167-5699(97)01199-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The ability of superantigens (SAgs) to activate the immune system suggests that they may play a role in the course of autoimmune disorders. Here, Joel Schiffenbauer and colleagues review evidence from animal models of autoimmunity, as well as human data that support this hypothesis, and propose a model for SAg involvement in autoimmune disorders.

引用

收藏

页码：117 / 120

页数：4

相关论文

共 42 条

[21] TOXIC SHOCK SYNDROME TOXIN-SECRETING STAPHYLOCOCCUS-AUREUS IN KAWASAKI SYNDROME [J].

LEUNG, DYM ;

MEISSNER, HC ;

FULTON, DR ;

MURRAY, DL ;

KOTZIN, BL ;

SCHLIEVERT, PM .

LANCET, 1993, 342 (8884) :1385-1388

[22] RESTRICTED T-CELL RECEPTOR V-BETA GENE USAGE IN THE SKIN OF PATIENTS WITH GUTTATE AND CHRONIC PLAQUE PSORIASIS [J].

LEWIS, HM ;

BAKER, BS ;

BOKTH, S ;

POWLES, AV ;

GARIOCH, JJ ;

VALDIMARSSON, H ;

FRY, L .

BRITISH JOURNAL OF DERMATOLOGY, 1993, 129 (05) :514-520

[23] THE STAPHYLOCOCCAL ENTEROTOXINS AND THEIR RELATIVES [J].

MARRACK, P ;

KAPPLER, J .

SCIENCE, 1990, 248 (4956) :705-711

[24]

MEHINDATE K, 1994, J BIOL CHEM, V269, P32063

[25] THE STAPHYLOCOCCAL TOXIC SHOCK SYNDROME TOXIN-1 TRIGGERS B-CELL PROLIFERATION AND DIFFERENTIATION VIA MAJOR HISTOCOMPATIBILITY COMPLEX-UNRESTRICTED COGNATE T/B-CELL INTERACTION [J].

MOURAD, W ;

SCHOLL, P ;

DIAZ, A ;

GEHA, R ;

CHATILA, T .

JOURNAL OF EXPERIMENTAL MEDICINE, 1989, 170 (06) :2011-2022

[26] ENGAGEMENT OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II MOLECULES BY SUPERANTIGEN INDUCES INFLAMMATORY CYTOKINE GENE-EXPRESSION IN HUMAN RHEUMATOID FIBROBLAST-LIKE SYNOVIOCYTES [J].

MOURAD, W ;

MEHINDATE, K ;

SCHALL, TJ ;

MCCOLL, SR .

JOURNAL OF EXPERIMENTAL MEDICINE, 1992, 175 (02) :613-616

[27]

ORIGUCHI T, 1995, CLIN EXP IMMUNOL, V99, P345

[28] EVIDENCE FOR THE EFFECTS OF A SUPERANTIGEN IN RHEUMATOID-ARTHRITIS [J].

PALIARD, X ;

WEST, SG ;

LAFFERTY, JA ;

CLEMENTS, JR ;

KAPPLER, JW ;

MARRACK, P ;

KOTZIN, BL .

SCIENCE, 1991, 253 (5017) :325-329

[29]

PIETRA BA, 1994, J IMMUNOL, V153, P1881

[30] DIFFERENTIAL INDUCTION OF TUMOR-NECROSIS-FACTOR-ALPHA IN MURINE AND HUMAN-LEUKOCYTES BY MYCOPLASMA ARTHRITIDIS-DERIVED SUPERANTIGEN [J].

RINK, L ;

NICKLAS, W ;

ALVAREZOSSORIO, L ;

KOESTER, M ;

KIRCHNER, H .

INFECTION AND IMMUNITY, 1994, 62 (02) :462-467

← 1 2 3 4 5 →