Hepatitis B virus taxonomy and hepatitis B virus genotypes

被引：248

作者：

Schaefer, Stephan ^{[1
]}

机构：

[1] Univ Rostock, Inst Med Mikrobiol Virol & Hyg, Abt Virol, D-18057 Rostock, Germany

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2007年 / 13卷 / 01期

关键词：

orthohepadnavirus; avihepadnavirus; hepatitis B virus; genotype; subgenotype; recombination;

D O I：

10.3748/wjg.v13.i1.14

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Hepatitis B virus (HBV) is a member of the hepadnavirus family. Hepadnaviruses can be found in both mammals (orthohepadnaviruses) and birds (avihepadnaviruses). The genetic variability of HBV is very high. There are eight genotypes of HBV and three clades of HBV isolates from apes that appear to be additional genotypes of HBV. Most genotypes are now divided into subgenotypes with distinct virological and epidemiological properties. In addition, recombination among HBV genotypes increases the variability of HBV. This review summarises current knowledge of the epidemiology of genetic variability in hepadnaviruses and, due to rapid progress in the field, updates several recent reviews on HBV genotypes and subgenotypes. (c) 2007 The WJG Press. All rights reserved.

引用

页码：14 / 21

页数：8

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