The cross-coupling reaction of arylboronic acids with chloropyridines and electron-deficient chloroarenes catalyzed by a polymer-bound palladium complex

被引：85

作者：

Inada, K ^{[1
]}

Miyaura, N ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Engn, Div Mol Chem, Sapporo, Hokkaido 0608628, Japan

来源：

TETRAHEDRON | 2000年 / 56卷 / 44期

关键词：

coupling reactions; boron compounds; biaryl; polymer support;

D O I：

10.1016/S0040-4020(00)00815-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The cross-coupling reaction of tolylboronic acids (1.3 equiv.) with chloropyridines, chloroquinoline, or activated chloroarenes having an electron-withdrawing group was carried out in toluene at 80 degreesC in the presence of a polymer-bound PdCl2 catalyst (3 mol%) and aqueous 2 hi K3PO4 (2.6 equiv.). The palladium-phosphine complex supported on a polystyrene-PPh2 resin was reused with no significant decrease in activity. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：8661 / 8664

页数：4

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