Cultivation and grafting of human keratinocytes on a poly(hydroxyethyl methacrylate) support to the wound bed:: a clinical study

被引：36

作者：

Dvoránková, B

Smetana, K

Königová, R

Singerová, H

Vacík, J

Jelínková, M

Kapounková, Z

Zahradník, M

机构：

[1] Charles Univ, Fac Med 1, Inst Anat, CZ-12800 Prague, Czech Republic

[2] Charles Univ, Fac Med 3, Prague Burn Ctr, Prague, Czech Republic

[3] Acad Sci Czech Republ, Inst Macromol Chem, Prague, Czech Republic

来源：

BIOMATERIALS | 1998年 / 19卷 / 1-3期

关键词：

keratinocytes; burn injury; cell transplantation; tissue engineering; cytokeratins;

D O I：

10.1016/S0142-9612(97)00176-2

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Cultured epithelial sheets on a textile support are used for the treatment of seriously burned patients. In this study we demonstrate a new procedure for the grafting of keratinocytes directly on a polymer cultivation support. This procedure is much easier in comparison with classical techniques, and encouraging results of clinical trials demonstrate the improved healing of the wound bed after the use of this procedure. There is no difference in the cytokeratine pattern (LP-34, cytokeratin-10) of the reconstructed epidermis and normal human skin. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：141 / 146

页数：6

共 16 条

[11] A RECOMBINED SKIN COMPOSED OF HUMAN KERATINOCYTES CULTURED ON CELL-FREE PIG DERMIS [J].