Stereoselective enzymatic hydrolysis of dimethyl meso-piperidine-3,5-dicarboxylates

被引：20

作者：

Danieli, B ^{[1
]}

Lesma, G ^{[1
]}

Passarella, D ^{[1
]}

Silvani, A ^{[1
]}

机构：

[1] UNIV MILAN,DIPARTIMENTO CHIM ORGAN & IND,CNR,CTR STUDIO SOSTANZE ORGAN NAT,I-20133 MILAN,ITALY

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 02期

关键词：

D O I：

10.1016/0957-4166(96)00002-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Desymmetrization of dimethyl meso-piperidine-3,5-dicarboxylates 3a-c with pig liver esterase (PLE), lipase from Candida cylindracea (CCL) and porcine pancreatic lipase (PPL) is described. The enantioselectivities of the enzymatic transformations and the absolute configurations of the resulting half-esters 2a-c were determined.

引用

页码：345 / 348

页数：4

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