Synthesis of poly(solketal methacrylate)-block-poly(2-(dimethylamino)ethyl methacrylate) and preparation of nanospheres with cross-linked shells

被引：73

作者：

Zhang, ZR ^{[1
]}

Liu, GJ ^{[1
]}

Bell, S ^{[1
]}

机构：

[1] Univ Calgary, Dept Chem, 2500 Univ Dr NW, Calgary, AB T2N 1N4, Canada

来源：

MACROMOLECULES | 2000年 / 33卷 / 21期

关键词：

D O I：

10.1021/ma000781o

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Living free radical polymerization was used to prepare poly(solketal methacrylate)-block-poly(2-(dimethylamino)ethyl methacrylate) or PSMA-b-PDMAEMA. A diblock with 105 SMA units and 122 DMAEMA units formed spherical micelles with PDMAEMA coronas and PSMA cores in water with 5 vol % THF. Nanospheres with cross-linked shells were obtained by cross-linking the PDMAEMA coronas with 1,2-bis(2'-iodoethoxyl)ethane (BIEE). The cores of the nanospheres were made hydrophilic by hydrolyzing the acetonide groups of PSMA.

引用

页码：7877 / 7883

页数：7