Human Brown Adipose Tissue

被引:299
作者
Enerback, Sven [1 ]
机构
[1] Univ Gothenburg, Inst Biomed, Dept Med & Clin Genet, SE-40530 Gothenburg, Sweden
基金
瑞典研究理事会;
关键词
DIET-INDUCED THERMOGENESIS; ADULT HUMANS; OBESITY; UCP1; FAT;
D O I
10.1016/j.cmet.2010.03.008
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The BAT organ is unique in that it has evolved to safely dissipate large amounts of chemical energy a quality that might be harnessed to help humans deal with a dangerously hypercaloric environment and still remain in good health.
引用
收藏
页码:248 / 252
页数:5
相关论文
共 27 条
  • [11] HIMMSHAGEN J, 1979, CAN MED ASSOC J, V121, P1361
  • [12] THE OCCURRENCE OF BROWN ADIPOSE-TISSUE IN OUTDOOR WORKERS
    HUTTUNEN, P
    HIRVONEN, J
    KINNULA, V
    [J]. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY AND OCCUPATIONAL PHYSIOLOGY, 1981, 46 (04): : 339 - 345
  • [13] Marsupial uncoupling protein 1 sheds light on the evolution of mammalian nonshivering thermogenesis
    Jastroch, M.
    Withers, K. W.
    Taudien, S.
    Frappell, P. B.
    Helwig, M.
    Fromme, T.
    Hirschberg, V.
    Heldmaier, G.
    McAllan, B. M.
    Firth, B. T.
    Burmester, T.
    Platzer, M.
    Klingenspor, M.
    [J]. PHYSIOLOGICAL GENOMICS, 2008, 32 (02) : 161 - 169
  • [14] Functional characterisation of UCP1 in the common carp: uncoupling activity in liver mitochondria and cold-induced expression in the brain
    Jastroch, Martin
    Buckingham, Julie A.
    Helwig, Michael
    Klingenspor, Martin
    Brand, Martin D.
    [J]. JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY, 2007, 177 (07) : 743 - 752
  • [15] LEAN MEJ, 1986, INT J OBESITY, V10, P219
  • [16] Lichtenbelt WDV, 2009, NEW ENGL J MED, V360, P1500, DOI 10.1056/NEJMoa0808718
  • [17] UPTAKE OF GLUCOSE AND RELEASE OF FATTY-ACIDS AND GLYCEROL BY RAT BROWN ADIPOSE-TISSUE INVIVO
    MA, SWY
    FOSTER, DO
    [J]. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1986, 64 (05) : 609 - 614
  • [18] Quantitative MRI-based temperature mapping based on the proton resonant frequency shift: Review of validation studies
    McDannold, N
    [J]. INTERNATIONAL JOURNAL OF HYPERTHERMIA, 2005, 21 (06) : 533 - 546
  • [19] Thermoregulation: What role for UCPs in mammals and birds?
    Mozo, J
    Emre, Y
    Bouillaud, F
    Ricquier, D
    Criscuolo, F
    [J]. BIOSCIENCE REPORTS, 2005, 25 (3-4) : 227 - 249
  • [20] Expression of Uncoupling Protein 1 in Mouse Brown Adipose Tissue Is Thyroid Hormone Receptor-β Isoform Specific and Required for Adaptive Thermogenesis
    Ribeiro, Miriam O.
    Bianco, Suzy D. C.
    Kaneshige, Masahiro
    Schultz, James J.
    Cheng, Sheue-yann
    Bianco, Antonio C.
    Brent, Gregory A.
    [J]. ENDOCRINOLOGY, 2010, 151 (01) : 432 - 440