Kleisins: A superfamily of bacterial and eukaryotic SMC protein partners

被引:191
作者
Schleiffer, A [1 ]
Kaitna, S [1 ]
Maurer-Stroh, S [1 ]
Glotzer, M [1 ]
Nasmyth, K [1 ]
Eisenhaber, F [1 ]
机构
[1] Res Inst Mol Pathol, A-1030 Vienna, Austria
关键词
D O I
10.1016/S1097-2765(03)00108-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We describe a superfamily of eukaryotic and prokaryotic proteins (kleisins) that includes ScpA, Scc1, Rec8, and Barren. Scc1 interacts with SMC proteins through N- and C-terminal domains to form a ring-like structure. Since these are the only domains conserved among kleisins, we suggest that ring formation with SMC proteins may define this family.
引用
收藏
页码:571 / 575
页数:5
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