Protein binding between PcrG-PcrV and PcrH-PopB/PopD encoded by the pcrGVH-popBD operon of the Pseudomonas aeruginosa type III secretion system

被引:29
作者
Allmond, LR
Karaca, TJ
Nguyen, VN
Nguyen, T
Wiener-Kronish, JP
Sawa, T
机构
[1] Univ Calif San Francisco, Sch Med, Dept Anesthesia & Perioperat Care, San Francisco, CA 94143 USA
[2] Western Univ Hlth Sci, Coll Osteopath Med Pacific, Pomona, CA USA
关键词
D O I
10.1128/IAI.71.4.2230-2233.2003
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Of the proteins encoded by the pcrGVH-popBD operon of the Pseudomonas aeruginosa type III secretion system, PcrG bound to PcrV and PcrH bound to PopB/PopD. In addition, Yersinia LcrG bound to PcrV, and Yersinia LcrH bound to PopD. The results imply a highly functional conservation of type III secretion between P. aeruginosa and Yersinia species.
引用
收藏
页码:2230 / 2233
页数:4
相关论文
共 40 条
[1]   Recombinant V antigen protects mice against pneumonic and bubonic plague caused by F1-capsule-positive and -negative strains of Yersinia pestis [J].
Anderson, GW ;
Leary, SEC ;
Williamson, ED ;
Titball, RW ;
Welkos, SL ;
Worsham, PL ;
Friedlander, AM .
INFECTION AND IMMUNITY, 1996, 64 (11) :4580-4585
[2]   ANALYSIS OF THE V-ANTIGEN LCRGVH-YOPBD OPERON OF YERSINIA-PSEUDOTUBERCULOSIS - EVIDENCE FOR A REGULATORY ROLE OF LCRH AND LCRV [J].
BERGMAN, T ;
HAKANSSON, S ;
FORSBERG, A ;
NORLANDER, L ;
MACELLARO, A ;
BACKMAN, A ;
BOLIN, I ;
WOLFWATZ, H .
JOURNAL OF BACTERIOLOGY, 1991, 173 (05) :1607-1616
[3]  
BURROWS TW, 1956, BRIT J EXP PATHOL, V37, P481
[4]  
BURROWS TW, 1958, BRIT J EXP PATHOL, V39, P278
[5]   Assembly and function of type III secretory systems [J].
Cornelis, GR ;
Van Gijsegem, F .
ANNUAL REVIEW OF MICROBIOLOGY, 2000, 54 :735-774
[6]   The Yersinia Yop virulon: A bacterial system for subverting eukaryotic cells [J].
Cornelis, GR ;
WolfWatz, H .
MOLECULAR MICROBIOLOGY, 1997, 23 (05) :861-867
[7]   Roles of LcrG and LcrV during type III targeting of effector Yops by Yersinia enterocolitica [J].
DeBord, KL ;
Lee, VT ;
Schneewind, O .
JOURNAL OF BACTERIOLOGY, 2001, 183 (15) :4588-4598
[8]   ExoU expression by Pseudomonas aeruginosa correlates with acute cytotoxicity and epithelial injury [J].
FinckBarbancon, V ;
Goranson, J ;
Zhu, L ;
Sawa, T ;
WienerKronish, JP ;
Fleiszig, SMJ ;
Wu, C ;
MendeMueller, L ;
Frank, DW .
MOLECULAR MICROBIOLOGY, 1997, 25 (03) :547-557
[9]   Pseudomonas aeruginosa-mediated cytotoxicity and invasion correlate with distinct genotypes at the loci encoding exoenzyme S [J].
Fleiszig, SMJ ;
WienerKronish, JP ;
Miyazaki, H ;
Vallas, V ;
Mostov, KE ;
Kanada, D ;
Sawa, T ;
Yen, TSB ;
Frank, DW .
INFECTION AND IMMUNITY, 1997, 65 (02) :579-586
[10]   A study of the YopD-LcrH interaction from Yersinia pseudotuberculosis reveals a role for hydrophobic residues within the amphipathic domain of YopD [J].
Francis, MS ;
Aili, M ;
Wiklund, ML ;
Wolf-Watz, H .
MOLECULAR MICROBIOLOGY, 2000, 38 (01) :85-102