Protein binding between PcrG-PcrV and PcrH-PopB/PopD encoded by the pcrGVH-popBD operon of the Pseudomonas aeruginosa type III secretion system

被引:29
作者
Allmond, LR
Karaca, TJ
Nguyen, VN
Nguyen, T
Wiener-Kronish, JP
Sawa, T
机构
[1] Univ Calif San Francisco, Sch Med, Dept Anesthesia & Perioperat Care, San Francisco, CA 94143 USA
[2] Western Univ Hlth Sci, Coll Osteopath Med Pacific, Pomona, CA USA
关键词
D O I
10.1128/IAI.71.4.2230-2233.2003
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Of the proteins encoded by the pcrGVH-popBD operon of the Pseudomonas aeruginosa type III secretion system, PcrG bound to PcrV and PcrH bound to PopB/PopD. In addition, Yersinia LcrG bound to PcrV, and Yersinia LcrH bound to PopD. The results imply a highly functional conservation of type III secretion between P. aeruginosa and Yersinia species.
引用
收藏
页码:2230 / 2233
页数:4
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共 40 条
[11]   The type III secretion chaperone LcrH co-operates with YopD to establish a negative, regulatory loop for control of Yop synthesis in Yersinia pseudotuberculosis [J].
Francis, MS ;
Lloyd, SA ;
Wolf-Watz, H .
MOLECULAR MICROBIOLOGY, 2001, 42 (04) :1075-1093
[12]   The exoenzyme S regulon of Pseudomonas aeruginosa [J].
Frank, DW .
MOLECULAR MICROBIOLOGY, 1997, 26 (04) :621-629
[13]   Generation and characterization of a protective monoclonal antibody to Pseudomonas aeruginosa PcrV [J].
Frank, DW ;
Vallis, A ;
Wiener-Kronish, JP ;
Roy-Burman, A ;
Spack, EG ;
Mullaney, BP ;
Megdoud, M ;
Marks, JD ;
Fritz, R ;
Sawa, T .
JOURNAL OF INFECTIOUS DISEASES, 2002, 186 (01) :64-73
[14]   Functional conservation of the effector protein translocators PopB/YopB and PopD/YopD of Pseudomonas aeruginosa and Yersinia pseudotuberculosis [J].
Frithz-Lindsten, E ;
Holmström, A ;
Jacobsson, L ;
Soltani, M ;
Olsson, J ;
Rosqvist, R ;
Forsberg, A .
MOLECULAR MICROBIOLOGY, 1998, 29 (05) :1155-1165
[15]   Type III secretion machines:: Bacterial devices for protein delivery into host cells [J].
Galán, JE ;
Collmer, A .
SCIENCE, 1999, 284 (5418) :1322-1328
[16]  
HAKANSSON S, 1993, INFECT IMMUN, V61, P71
[17]   The YopB protein of Yersinia pseudotuberculosis is essential for the translocation of Yop effector proteins across the target cell plasma membrane and displays a contact-dependent membrane disrupting activity [J].
Hakansson, S ;
Schesser, K ;
Persson, C ;
Galyov, EE ;
Rosqvist, R ;
Homble, F ;
WolfWatz, H .
EMBO JOURNAL, 1996, 15 (21) :5812-5823
[18]   Regions of Yersinia pestis V antigen that contribute to protection against plague identified by passive and active immunization [J].
Hill, J ;
Leary, SEC ;
Griffin, KF ;
Williamson, ED ;
Titball, RW .
INFECTION AND IMMUNITY, 1997, 65 (11) :4476-4482
[19]   LcrV is a channel size-determining component of the Yop effector translocon of Yersinia [J].
Holmström, A ;
Olsson, J ;
Cherepanov, P ;
Maier, E ;
Nordfelth, R ;
Pettersson, J ;
Benz, R ;
Wolf-Watz, H ;
Forsberg, Å .
MOLECULAR MICROBIOLOGY, 2001, 39 (03) :620-632
[20]   Type III protein secretion systems in bacterial pathogens of animals and plants [J].
Hueck, CJ .
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 1998, 62 (02) :379-+