Assessment of cognitive functions in severely paralysed and severely brain-damaged patients: neuropsychological and electrophysiological methods

被引:59
作者
Neumann, N [1 ]
Kotchoubey, B [1 ]
机构
[1] Univ Tubingen, Inst Med Psychol & Behav Neurobiol, D-72074 Tubingen, Germany
来源
BRAIN RESEARCH PROTOCOLS | 2004年 / 14卷 / 01期
关键词
neuropsychological assessment; event-related potentials; locked-in syndrome; persistent vegetative state; minimally conscious state;
D O I
10.1016/j.brainresprot.2004.09.001
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A systematic neuropsychological assessment technique is described for use with severely physically disabled individuals, possibly with combined motor and cognitive disorders. Target neurological conditions may be, e.g., an incomplete locked-in state, a minimally conscious state, or severe combinations of paralysis, agnosia, and apraxia. Neuropsychological assessment in these patients is difficult, because standard neuropsychological tests require fast motor responses, which can be manual, verbal, or both. To assess the cognitive status of patients with residual motor function, tests have been applied that can be answered by a binary (yes/no) signal and whose outcomes were not based on reaction times. Further, a battery of neurophysiological examination procedures based on event-related brain potentials has been developed. These procedures can be performed directly at a patient's bedside (at home or in a hospital) and applied for assessment of cognitive functions even in patients without residual motor function. (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码:25 / 36
页数:12
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