Biotransformation of progesterone by the green alga Chlorella emersonii C211-8h

被引：9

作者：

DellaGreca, M

Fiorentino, A

Pinto, G

Pollio, A

Previtera, L

机构：

[1] UNIV NAPLES FEDERICO II,DIPARTIMENTO CHIM ORGAN & BIOL,I-80134 NAPLES,ITALY

[2] UNIV NAPLES FEDERICO II,DIPARTIMENTO BIOL VEGETALE,I-80139 NAPLES,ITALY

来源：

PHYTOCHEMISTRY | 1996年 / 41卷 / 06期

关键词：

Chlorella emersonii; C211-8h; progesterone; biotransformation; hydroxyprogesterones; testololactone;

D O I：

10.1016/0031-9422(95)00786-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

2 beta-Hydroxyprogesterone, 6 beta-hydroxyprogesterone, 9 alpha-hydroxyprogesterone, 14 alpha-hydroxyprogesterone, 16 alpha-hydroxyprogesterone and 21-hydroxyprogesterone are the main bioproducts in the progesterone bioconversion by axenic cultures of Chlorella emersonii C211-8h. After 30 days 6 beta,9 alpha-dihydroxyprogesterone, 6 beta,21-dihydroxyprogesterone and 16 alpha,21-dihydroxyprogesterone are also formed. In acid conditions the reaction is slower and 2 beta-hydroxyprogesterone and 16 alpha-hydroxyprogesterone have not been found among the bioproducts. In hyperhaline conditions the yields are generally lower and testololactone is also formed.

引用

页码：1527 / 1529

页数：3

共 9 条

[1] TRANSFORMATION OF STEROIDS BY ALGAE [J].