An assessment of the technique of simultaneous cooling in conjunction with microwave heating for organic synthesis

被引：72

作者：

Leadbeater, NE ^{[1
]}

Pillsbury, SJ ^{[1
]}

Shanahan, E ^{[1
]}

Williams, VA ^{[1
]}

机构：

[1] Univ Connecticut, Dept Chem, Storrs, CT 06269 USA

来源：

TETRAHEDRON | 2005年 / 61卷 / 14期

关键词：

microwave; water; heck coupling; Diels-Alder reaction; Michael addition;

D O I：

10.1016/j.tet.2005.01.105

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In the light of the controversy in the area and since reports using simultaneous cooling in conjunction with microwave heating are appearing in the literature, we were keen to assess the methodology, looking at temperature measurement issues as well as the use of the technique in three classes of reaction, namely a Heck coupling, a Diels-Alder cycloaddition and a Michael addition. We present our initial findings here. (c) 2005 Elsevier Ltd. All rights reserved.

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收藏

页码：3565 / 3585

页数：21

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