Biocatalytic transformations in ionic liquids

被引：558

作者：

van Rantwijk, F ^{[1
]}

Lau, RM ^{[1
]}

Sheldon, RA ^{[1
]}

机构：

[1] Delft Univ Technol, Lab Biocatalysis & Organ Chem, NL-2628 BL Delft, Netherlands

来源：

TRENDS IN BIOTECHNOLOGY | 2003年 / 21卷 / 03期

关键词：

D O I：

10.1016/S0167-7799(03)00008-8

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Room temperature ionic liquids are non-volatile, thermally stable and highly polar; they are also moderately hydrophilic solvents. Here, we discuss their use as reaction media for biocatalysis. Enzymes of widely diverging types are catalytically active in ionic liquids or aqueous biphasic ionic liquid systems. Lipases, in particular, maintain their activity in anhydrous ionic liquid media; the (enantio)selectivity and operational stability are often better than in traditional media. The unconventional solvent properties of ionic liquids have been exploited in biocatalyst recycling and product recovery schemes that are not feasible with traditional solvent systems.

引用

页码：131 / 138

页数：8

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