Myeloproliferative neoplasms: Morphology and clinical practice

被引：33

作者：

Barbui, Tiziano ^{[1
]}

Thiele, Juergen ^{[2
]}

Vannucchi, Alessandro M. ^{[3
]}

Tefferi, Ayalew ^{[4
]}

机构：

[1] Papa Giovanni XXIII Hosp, Res Fdn, Bergamo, Italy

[2] Univ Cologne, Inst Pathol, Joseph Stelzmann Str 9, Cologne, Germany

[3] Univ Florence, Dept Expt & Clin Med, Florence, Italy

[4] Mayo Clin, Div Hematol, Rochester, MN USA

来源：

AMERICAN JOURNAL OF HEMATOLOGY | 2016年 / 91卷 / 04期

关键词：

BONE-MARROW FIBROSIS; CHRONIC IDIOPATHIC MYELOFIBROSIS; INTERNATIONAL WORKING GROUP; ESSENTIAL THROMBOCYTHEMIA; POLYCYTHEMIA-VERA; REFRACTORY-ANEMIA; RINGED SIDEROBLASTS; DIAGNOSTIC-CRITERIA; HISTOLOGICAL CRITERIA; BLAST-TRANSFORMATION;

D O I：

10.1002/ajh.24288

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In myeloproliferative neoplasms (MPNs), controversy persists regarding the usefulness and reproducibility of bone marrow (BM) features. Disagreements concerning the WHO classification are mainly focused on the discrimination between essential thrombocythemia (ET) and prefibrotic/early primary myelofibrosis (prePMF) and prodromal polycythemia vera (PV). Criticism mostly refers to lack of standardization of distinctive BM features precluding correct morphological pattern recognition. The distinction between WHO-defined ET and prePMF is not trivial because outcome is significantly worse in prePMF. Morphology was generally considered to be non-specific for the diagnosis of PV. Recent studies have revealed under-diagnosis of morphologically and biologically consistent PV. Am. J. Hematol. 91:430-433, 2016. (c) 2015 Wiley Periodicals, Inc.

引用

收藏

页码：430 / 433

页数：4

相关论文

共 74 条

[11] Essential thrombocythemia vs. early/prefibrotic myelofibrosis: Why does it matter [J].

Barosi, Giovanni .

BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY, 2014, 27 (02) :129-140

[12] Evidence that Prefibrotic Myelofibrosis Is Aligned along a Clinical and Biological Continuum Featuring Primary Myelofibrosis [J].

Barosi, Giovanni ;

Rosti, Vittorio ;

Bonetti, Elisa ;

Campanelli, Rita ;

Carolei, Adriana ;

Catarsi, Paolo ;

Isgro, Antonina M. ;

Lupo, Letizia ;

Massa, Margherita ;

Poletto, Valentina ;

Viarengo, Gianluca ;

Villani, Laura ;

Magrini, Umberto .

PLOS ONE, 2012, 7 (04)

[13] The JAK2-V617F mutation and essential thrombocythemia features in a subset of patients with refractory anemia with ring sideroblasts (RARS) [J].

Boissinot, Marjorie ;

Garand, Richard ;

Hamidou, Mohamed ;

Hermouet, Sylvie .

BLOOD, 2006, 108 (05) :1781-1782

[14] MYELOFIBROSIS IN CHRONIC MYELOPROLIFERATIVE DISORDERS - INCIDENCE AMONG SUBTYPES ACCORDING TO THE HANNOVER CLASSIFICATION [J].

BUHR, T ;

GEORGII, A ;

CHORITZ, H .

PATHOLOGY RESEARCH AND PRACTICE, 1993, 189 (02) :121-132

[15] Evolution of myelofibrosis in chronic idiopathic myelofibrosis as evidenced in sequential bone marrow biopsy specimens [J].

Buhr, T ;

Büsche, G ;

Choritz, H ;

Länger, F ;

Kreipe, H .

AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2003, 119 (01) :152-158

[16] Blast transformation and fibrotic progression in polycythemia vera and essential thrombocythemia: a literature review of incidence and risk factors [J].

Cerquozzi, S. ;

Tefferi, A. .

BLOOD CANCER JOURNAL, 2015, 5 :e366-e366

[17] Myelofibrosis with myeloid metaplasia: Diagnosis, prognostic factors, and staging [J].

Cervantes, F ;

Barosi, G .

SEMINARS IN ONCOLOGY, 2005, 32 (04) :395-402

[18] New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment [J].

Cervantes, Francisco ;

Dupriez, Brigitte ;

Pereira, Arturo ;

Passamonti, Francesco ;

Reilly, John T. ;

Morra, Enrica ;

Vannucchi, Alessandro M. ;

Mesa, Ruben A. ;

Demory, Jean-Loup ;

Barosi, Giovanni ;

Rumi, Elisa ;

Tefferi, Ayalew .

BLOOD, 2009, 113 (13) :2895-2901

[19] INTERFERON-ALPHA-INDUCED MORPHOLOGICAL-CHANGES OF MEGAKARYOCYTES - A HISTOMORPHOMETRICAL STUDY ON BONE-MARROW BIOPSIES IN CHRONIC MYELOPROLIFERATIVE DISORDERS WITH EXCESSIVE THROMBOCYTOSIS [J].

CHOTT, A ;

GISSLINGER, H ;

THIELE, J ;

FRITZ, E ;

LINKESCH, W ;

RADASZKIEWICZ, T ;

LUDWIG, H .

BRITISH JOURNAL OF HAEMATOLOGY, 1990, 74 (01) :10-16

[20] Diagnosis according to World Health Organization determines the long-term prognosis in patients with myeloproliferative neoplasms treated with anagrelide: Results of a prospective long-term follow-up [J].

Ejerblad, Elisabeth ;

Kvasnicka, Hans M. ;

Thiele, Juergen ;

Andreasson, Bjorn ;

Bjorkholm, Magnus ;

Lofvenberg, Eva ;

Markevarn, Berit ;

Merup, Mats ;

Nilssson, Lars ;

Palmblad, Jan ;

Samuelsson, Jan ;

Birgegard, Gunnar .

HEMATOLOGY, 2013, 18 (01) :8-13

← 1 2 3 4 5 6 7 8 →