Genomics and gene therapy - Artificial chromosomes coming to life

被引:46
作者
Willard, HF [1 ]
机构
[1] Case Western Reserve Univ, Dept Genet, Cleveland, OH 44106 USA
[2] Case Western Reserve Univ, Ctr Human Genet, Cleveland, OH 44106 USA
[3] Univ Hosp Cleveland, Res Inst, Cleveland, OH 44106 USA
关键词
D O I
10.1126/science.290.5495.1308
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:1308 / 1309
页数:2
相关论文
共 34 条
[1]   Artificial chromosomes: ideal vectors? [J].
Brown, WRA ;
Mee, PJ ;
Shen, MH .
TRENDS IN BIOTECHNOLOGY, 2000, 18 (05) :218-223
[2]   CLONING OF LARGE SEGMENTS OF EXOGENOUS DNA INTO YEAST BY MEANS OF ARTIFICIAL CHROMOSOME VECTORS [J].
BURKE, DT ;
CARLE, GF ;
OLSON, MV .
SCIENCE, 1987, 236 (4803) :806-812
[3]   The potential of extrachromosomal replicating vectors for gene therapy [J].
Calos, MP .
TRENDS IN GENETICS, 1996, 12 (11) :463-466
[4]   Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease [J].
Cavazzana-Calvo, M ;
Hacein-Bey, S ;
Basile, CD ;
Gross, F ;
Yvon, E ;
Nusbaum, P ;
Selz, F ;
Hue, C ;
Certain, S ;
Casanova, JL ;
Bousso, P ;
Le Deist, F ;
Fischer, A .
SCIENCE, 2000, 288 (5466) :669-672
[5]   Centromere DNA dynamics: Latent centromeres and neocentromere formation [J].
Choo, KHA .
AMERICAN JOURNAL OF HUMAN GENETICS, 1997, 61 (06) :1225-1233
[6]   Genetic definition and sequence analysis of Arabidopsis centromeres [J].
Copenhaver, GP ;
Nickel, K ;
Kuromori, T ;
Benito, MI ;
Kaul, S ;
Lin, XY ;
Bevan, M ;
Murphy, G ;
Harris, B ;
Parnell, LD ;
McCombie, WR ;
Martienssen, RA ;
Marra, M ;
Preuss, D .
SCIENCE, 1999, 286 (5449) :2468-2474
[7]   Something from nothing: The evolution and utility of satellite repeats [J].
Csink, AK ;
Henikoff, S .
TRENDS IN GENETICS, 1998, 14 (05) :200-204
[8]   Mammalian artificial chromosome formation from circular alphoid input DNA does not require telomere repeats [J].
Ebersole, TA ;
Ross, A ;
Clark, E ;
McGill, N ;
Schindelhauer, D ;
Cooke, H ;
Grimes, B .
HUMAN MOLECULAR GENETICS, 2000, 9 (11) :1623-1631
[9]  
GRIMES B, UNPUB
[10]   Formation of de novo centromeres and construction of first-generation human artificial microchromosomes [J].
Harrington, JJ ;
VanBokkelen, G ;
Mays, RW ;
Gustashaw, K ;
Willard, HF .
NATURE GENETICS, 1997, 15 (04) :345-355