Polymerase chain reaction in the management of disseminated adenovirus infection after stem cell transplantation

被引：7

作者：

Walls, T

Hawrami, K

Shingadia, D

Ushiro-Lumb, I

Shankar, A

机构：

[1] Royal London Hosp, Acad Dept Child Hlth, London E1 1BB, England

[2] Royal London Hosp, Dept Paediat Haematol Oncol, London E1 1BB, England

[3] St Bartholomews Hosp, Dept Virol, London, England

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2004年 / 23卷 / 12期

关键词：

adenovirus; pediatric; bone marrow transplantation; polymerase chain reaction;

D O I：

10.1097/01.inf.0000145407.56083.89

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report a 20-month-old child with disseminated adenovirus infection after a haploidentical T cell-depleted stem cell transplantation. This case demonstrates the value of polymerase chain reaction surveillance for early detection of adenovirus infection and the role of quantitative polymerase chain reaction for monitoring antiviral therapy. It also emphasizes the importance of T cell immunity in controlling disseminated adenovirus infection after stem cell transplantation.

引用

收藏

页码：1167 / 1169

页数：3

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